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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKD
All Species:
4.24
Human Site:
S681
Identified Species:
9.33
UniProt:
Q16760
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16760
NP_003639.2
1214
134525
S681
G
R
S
Q
R
K
V
S
K
S
P
C
E
K
L
Chimpanzee
Pan troglodytes
XP_001151474
1220
134870
A688
T
A
P
R
S
P
D
A
R
A
S
Y
G
H
S
Rhesus Macaque
Macaca mulatta
XP_001114920
1167
129871
L637
G
R
S
Q
R
K
V
L
K
S
P
C
E
K
L
Dog
Lupus familis
XP_543293
1324
146248
S791
G
R
S
L
R
K
V
S
K
S
P
C
E
K
L
Cat
Felis silvestris
Mouse
Mus musculus
NP_808314
1220
135190
A683
K
G
R
S
Q
R
K
A
S
R
A
P
C
E
K
Rat
Rattus norvegicus
XP_347259
1196
133109
A663
K
G
R
S
H
R
K
A
S
R
T
P
C
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507672
1254
138458
R721
T
A
P
R
S
P
D
R
R
T
S
G
V
F
S
Chicken
Gallus gallus
XP_001232791
1333
149344
R800
A
P
R
S
P
D
R
R
T
S
R
G
I
H
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693512
1148
127826
L623
C
A
M
L
N
E
K
L
D
S
L
V
K
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A8JQ65
1895
211641
A1355
L
F
G
F
D
H
L
A
S
A
E
K
D
K
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202627
1158
127377
P614
N
N
Q
S
A
K
V
P
D
S
G
S
T
K
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.2
93.4
85.1
N.A.
93.7
90.2
N.A.
66.9
63.9
N.A.
60.9
N.A.
34.8
N.A.
N.A.
53.3
Protein Similarity:
100
76.3
94.1
87.8
N.A.
96.4
93.3
N.A.
77.4
73.8
N.A.
71.6
N.A.
46.5
N.A.
N.A.
65.8
P-Site Identity:
100
0
93.3
93.3
N.A.
0
0
N.A.
0
6.6
N.A.
13.3
N.A.
6.6
N.A.
N.A.
26.6
P-Site Similarity:
100
26.6
93.3
93.3
N.A.
26.6
20
N.A.
20
6.6
N.A.
26.6
N.A.
33.3
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
28
0
0
10
0
0
37
0
19
10
0
0
10
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
28
19
0
0
% C
% Asp:
0
0
0
0
10
10
19
0
19
0
0
0
10
0
0
% D
% Glu:
0
0
0
0
0
10
0
0
0
0
10
0
28
19
19
% E
% Phe:
0
10
0
10
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
28
19
10
0
0
0
0
0
0
0
10
19
10
0
0
% G
% His:
0
0
0
0
10
10
0
0
0
0
0
0
0
19
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
19
0
0
0
0
37
28
0
28
0
0
10
10
46
19
% K
% Leu:
10
0
0
19
0
0
10
19
0
0
10
0
0
0
37
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
19
0
10
19
0
10
0
0
28
19
0
0
0
% P
% Gln:
0
0
10
19
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
28
28
19
28
19
10
19
19
19
10
0
0
0
0
% R
% Ser:
0
0
28
37
19
0
0
19
28
55
19
10
0
0
28
% S
% Thr:
19
0
0
0
0
0
0
0
10
10
10
0
10
0
0
% T
% Val:
0
0
0
0
0
0
37
0
0
0
0
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _